CP 55,244

CP 55,244是一种有机化合物，分子式C₂₆H₄₂O₃，属于人工合成的大麻素，具有镇痛药功能，由辉瑞公司开发^[1]，其对CB1的激动剂效果比HU-210更强^[2]。

CP 55,244

识别信息
IUPAC命名法 (2S,4S,4aS,6R,8aR)-6-(Hydroxymethyl)-4-[2-hydroxy-4-(2-methyloctan-2-yl)phenyl]-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-2-ol
CAS号	79678-32-3  Y
PubChem CID	133254
ChemSpider	117567
UNII	3HMR7H9HX8
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID701000660
化学信息
化学式	C26H42O3
摩尔质量	402.62 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像
SMILES CCCCCCC(C)(C)c1ccc(c(c1)O)[C@H]2C[C@H](C[C@@H]3[C@@H]2C[C@@H](CC3)CO)O
InChI InChI=1S/C26H42O3/c1-4-5-6-7-12-26(2,3)20-10-11-22(25(29)15-20)24-16-21(28)14-19-9-8-18(17-27)13-23(19)24/h10-11,15,18-19,21,23-24,27-29H,4-9,12-14,16-17H2,1-3H3/t18-,19-,21+,23+,24-/m1/s1 Key:ZAELPWSCABXXAB-QXASVXAKSA-N

另见

• CP 42,096
• CP 47,497
• CP 55,940

参考文献

1. Melvin LS, Milne GM, Johnson MR, Wilken GH, Howlett AC. Structure-activity relationships defining the ACD-tricyclic cannabinoids: cannabinoid receptor binding and analgesic activity. Drug Design and Discovery. November 1995, 13 (2): 155–66. PMID 8872458.
2. Griffin G, Wray EJ, Martin BR, Abood ME. Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum. British Journal of Pharmacology. October 1999, 128 (3): 684–8. PMC 1571656 . PMID 10516649. doi:10.1038/sj.bjp.0702806.

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